Neuroimaging - Brain Atlas


co-registered MR


highlighted atlas structures

Anatomical Brain Atlas

MIMneuro provides a comprehensive 3D Anatomical Brain Atlas defined on a high resolution MR. The Single Brain Atlas increases physician confidence by accurately defining the specific location of abnormalities with the click of a mouse. Additionally, the Single Brain Atlas provides pre-defined regions, saving time for quantitative analysis.

MIMneuro also provides a Multi-subject Probabilistic Brain Atlas, defined on high-resolution MR scans of ten subjects, which aids in quantitative region-based analysis by accounting for intersubject anatomic variability. Ten different levels of the probabilistic atlas can be selected allowing the user to place greater emphasis on anatomic specificity or sensitivity.1,2,3,4

Users can easily create and save their own custom regions of interest to use in comparisons.

An extensive database of age-appropriate volunteers with no neuropsychiatric symptoms is included with MIMneuro. Dynamic or static selections from the database can be easily made based on vendor and patient demographics, including age and gender, to increase the sensitivity of comparisons.

  1. Nelson AS, Piper JW, Friedland RP, Freeman B. Probabilistic Human Brain Atlas for functional imaging: Comparison to single brain atlases. J Nucl Med. 2007; 48 (Supplement 2):403P.
  2. Piper JW. Validation of an Artificial Neural Network Computer-Aided Diagnosis Scheme for Alzheimer’s Disease Using FDG-PET. Presented orally at the AMI/SMI Joint Molecular Imaging Conference, 2007.
  3. Piper JW, Nelson AS. Probabilistic Human Brain Atlas: Part 1, a surrogate for manual VOI definition. J Nucl Med. 2008;49 (Supplement 1):378p.
  4. Piper JW, Nelson AS. Probabilistic Human Brain Atlas: Part 2, validation with ADNI data. J Nucl Med. 2008;49 (Supplement 1):379p.

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